Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Idroxioleic acid

Name: Idroxioleic acid
Brand: TargetMol
SKU: T39265
Rating: 4.5 (1 reviews)

Copy Product Info

😃Good

Catalog No. T39265Cas No. 182370-45-2

Alias (R)-2-OHOA, (R)-2-Hydroxyoleic acid

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) is the R enantiomer of (Rac)-Idroxioleic acid. It is an orally active fatty acid recognized for its capacity to modulate lipid composition and membrane structure. With demonstrated antitumor activities, Idroxioleic acid is significant in cancer research.

Idroxioleic acid

Copy Product Info

😃Good

Catalog No. T39265Alias (R)-2-OHOA, (R)-2-Hydroxyoleic acidCas No. 182370-45-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,520	Inquiry	Inquiry

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description	Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) is the R enantiomer of (Rac)-Idroxioleic acid. It is an orally active fatty acid recognized for its capacity to modulate lipid composition and membrane structure. With demonstrated antitumor activities, Idroxioleic acid is significant in cancer research.
In vitro	(R)-2-Hydroxyoleic acid ((R)-2-OHOA), also known as idroxioleic acid, effectively inhibited the growth of the A549 lung adenocarcinoma cell line, demonstrating an IC50 value of 252 μM[1].
In vivo	(R)-2-Hydroxyoleic acid (R)-2-OHOA, administered orally at a dosage of 400 mg/kg daily for 21 days, led to a 20-25% decrease in tumor volume[1]. This outcome was observed in a study involving male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice, aged 5 weeks and weighing 30-35 g, which were injected with A549 human lung cancer cells[1].
Synonyms	(R)-2-OHOA, (R)-2-Hydroxyoleic acid

Chemical Properties

Molecular Weight	298.467
Formula	C₁₈H₃₄O₃
Cas No.	182370-45-2
Smiles	CCCCCCCC\C=C/CCCCCC[C@@H](O)C(O)=O
Relative Density.	0.957 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc