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6-NBDG

Name: 6-NBDG
Brand: TargetMol
SKU: T64361
Rating: 4.5 (1 reviews)

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Catalog No. T64361Cas No. 108708-22-1

6-NBDG, a fluorescent glucose analogue, can be used as a fluorescent probe.6-NBDG can be used for monitoring glucose transport and uptake. 6-NBDG can be used as for detecting macrophage-rich atherosclerotic plaques.

6-NBDG

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Purity: 98%

Catalog No. T64361Cas No. 108708-22-1

Pack Size	Price	Availability	Quantity
1 mg	$349	Backorder

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Purity:98%

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COA

Product Introduction

Bioactivity

Description

In vitro

Procedure
1. Mix the sample with RPMI without glucose, containing a final concentration of 200 μM 6-NBDG.
2. Use curved tweezers to embed the sample in the mixture and stretch the sample through a drop of agarose (40°C, 20 μL) placed on a preheated (40°C) glass slide.
3. Gently place another preheated glass slide on top of the sample so that the entire sample is embedded in the agarose-6-NBDG mixture.
4 Take confocal images using a confocal laser scanning microscope (Ex: 471 nm, Em: 500–600 nm).

Chemical Properties

Molecular Weight	342.26
Formula	C₁₂H₁₄N₄O₈
Cas No.	108708-22-1
Smiles	O=[N+]([O-])C1=CC=C(NC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)C2=NON=C21
Relative Density.	1.750 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

6-NBDG6NBDG