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Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | Inquiry | Inquiry |
| Description | Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. |
| In vitro | In BEL-7402 cells,waltonitone (10 μM, 25 μM; for 48 hours) results in an increment of sub-G1 population . Waltonitone (25 μM; for 48 hours) induces BEL-7402 cells apoptosis. In BEL-7402 cells, Waltonitone (25 μM; for 48 hours) can effectively activate caspase-3 . |
| In vivo | In male athymic mice (BALB/c nu/nu), Waltonitone administered intravenously (i.v.; 20 mg/kg or 50 mg/kg) at intervals of every other day for a duration of 16 days, effectively inhibits BEL-7402 tumor growth in vivo. |
| Molecular Weight | 440.7 |
| Formula | C30H48O2 |
| Cas No. | 1252676-55-3 |
| Smiles | C[C@]12C([C@]3([C@@](CO)(CC1)CC[C@@H](C)[C@@H]3C)[H])=CC[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CCC(=O)C5(C)C)[H])[H] |
| Relative Density. | 1.05 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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