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Vibostolimab (Synonyms: Vibostolimab (anti-TIGIT))

Catalog No. T35391 Copy Product Info
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Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melanoma.

Vibostolimab

Copy Product Info
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Catalog No. T35391
Synonyms Vibostolimab (anti-TIGIT)

Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melanoma.

Vibostolimab
Cas No. 2231305-30-7
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$228In StockIn Stock
5 mg$578In StockIn Stock
10 mg$928-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melanoma.
In vitro
Binding to TIGIT and blocking the interaction between TIGIT and its ligands (CD112 and CD155), Vibostolimab activates T lymphocytes, aiding in the destruction of tumor cells[1].
SynonymsVibostolimab (anti-TIGIT)
Reactivity
Human
Verified Activity
Immobilized Human TIGIT Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Vibostolimab. The EC50 is 18.61 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTIGIT/VSIG9/VSTM3
Chemical Properties
Molecular Weight147.08 kDa
Cas No.2231305-30-7
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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