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Thienodolin
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Catalog No. TN11084Cas No. 149127-27-5
Thienodolin, an alkaloid discovered in S. albogriseolus, enhances root and shoot growth in rice seedlings at a concentration of 4 µM, but at 40 µM, it inhibits growth. It suppresses LPS-induced nitric oxide (NO) production with an IC50 of 17.2 µM, diminishes LPS-induced rises in inducible NO synthase (iNOS) levels, and hinders LPS-induced IκB degradation in RAW 264.7 macrophages.
Thienodolin
😃Good
Catalog No. TN11084Cas No. 149127-27-5
Thienodolin, an alkaloid discovered in S. albogriseolus, enhances root and shoot growth in rice seedlings at a concentration of 4 µM, but at 40 µM, it inhibits growth. It suppresses LPS-induced nitric oxide (NO) production with an IC50 of 17.2 µM, diminishes LPS-induced rises in inducible NO synthase (iNOS) levels, and hinders LPS-induced IκB degradation in RAW 264.7 macrophages.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Thienodolin, an alkaloid discovered in S. albogriseolus, enhances root and shoot growth in rice seedlings at a concentration of 4 µM, but at 40 µM, it inhibits growth. It suppresses LPS-induced nitric oxide (NO) production with an IC50 of 17.2 µM, diminishes LPS-induced rises in inducible NO synthase (iNOS) levels, and hinders LPS-induced IκB degradation in RAW 264.7 macrophages. |
| Molecular Weight | 250.70 |
| Formula | C11H7ClN2OS |
| Cas No. | 149127-27-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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