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5-CNAC is an orally effective absorption enhancer with no inherent pharmacological activity. It significantly increases the gastrointestinal absorption efficiency of co-administered drugs (such as salmon calcitonin). By reversibly binding to peptide drugs in a non-covalent manner, 5-CNAC protects them from enzymatic degradation in the gastrointestinal tract and enhances lipid solubility, facilitating passive transepithelial transport without compromising intestinal epithelial integrity. It is useful in research as an adjuvant for oral peptide administration.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | 5-CNAC is an orally effective absorption enhancer with no inherent pharmacological activity. It significantly increases the gastrointestinal absorption efficiency of co-administered drugs (such as salmon calcitonin). By reversibly binding to peptide drugs in a non-covalent manner, 5-CNAC protects them from enzymatic degradation in the gastrointestinal tract and enhances lipid solubility, facilitating passive transepithelial transport without compromising intestinal epithelial integrity. It is useful in research as an adjuvant for oral peptide administration. |
| Molecular Weight | 313.78 |
| Formula | C15H20ClNO4 |
| Cas No. | 204852-67-5 |
| Smiles | O=C(O)CCCCCCCNC(=O)C1=CC(Cl)=CC=C1O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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