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Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. It significantly reduces systolic blood pressure in spontaneous hypertensive rat models with an ED50 value of 1.94 mg/kg. In renal hypertensive dog models, Mopidralazine hydrochloride acts more slowly but has a longer duration of effect and significantly less impact on heart rate increase. It is utilized in hypertension research.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. It significantly reduces systolic blood pressure in spontaneous hypertensive rat models with an ED50 value of 1.94 mg/kg. In renal hypertensive dog models, Mopidralazine hydrochloride acts more slowly but has a longer duration of effect and significantly less impact on heart rate increase. It is utilized in hypertension research. |
| Synonyms | MDL-899 |
| Molecular Weight | 309.8 |
| Formula | C14H20ClN5O |
| Cas No. | 86703-02-8 |
| Smiles | Cl.N=1N=C(C=CC1NN2C(=CC=C2C)C)N3CCOCC3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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