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Acyl-CoA oxidase (ACX) is a well-defined enzymatic protein that catalyzes the oxidation of fatty acyl-CoA substrates to 2-trans-enoyl-CoA intermediates, serving as a rate-limiting and essential step in the biosynthesis of jasmonic acid (JA), Acyl-CoA oxidase is particularly significant in model organisms such as Arabidopsis thaliana, Acyl-CoA oxidase contributes to lipid metabolism, stress signaling pathways, and the regulation of plant growth and defense responses.
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| Description | Acyl-CoA oxidase (ACX) is a well-defined enzymatic protein that catalyzes the oxidation of fatty acyl-CoA substrates to 2-trans-enoyl-CoA intermediates, serving as a rate-limiting and essential step in the biosynthesis of jasmonic acid (JA), Acyl-CoA oxidase is particularly significant in model organisms such as Arabidopsis thaliana, Acyl-CoA oxidase contributes to lipid metabolism, stress signaling pathways, and the regulation of plant growth and defense responses. |
| In vitro | Method: Structural and sequence comparisons were conducted between peroxisomal Acyl-CoA oxidase and mitochondrial acyl-CoA dehydrogenases. Result: The analyses revealed distinct mechanistic features controlling electron transfer, oxygen reactivity, and substrate discrimination between peroxisomal and mitochondrial β-oxidation enzymes[1]. |
| Synonyms | Acyl-CoA oxidase, ACO |
| Cas No. | 61116-22-1 |
| Color | Yellow |
| Appearance | Solid |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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