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CORT-108297 Enantiomer

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Catalog No. T9825Cas No. 1956435-30-5

CORT-108297 Enantiomer is an enantiomer of CORT-108297 which is an antagonist of the Glucocorticoid Receptor.

CORT-108297 Enantiomer

CORT-108297 Enantiomer

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Purity: 99.42%
Catalog No. T9825Cas No. 1956435-30-5
CORT-108297 Enantiomer is an enantiomer of CORT-108297 which is an antagonist of the Glucocorticoid Receptor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$82-In Stock
5 mg$188-In Stock
10 mg$277-In Stock
25 mg$413-In Stock
50 mg$580-In Stock
100 mg$791-In Stock
200 mg$1,070-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.42%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
CORT-108297 Enantiomer is an enantiomer of CORT-108297 which is an antagonist of the Glucocorticoid Receptor.
Chemical Properties
Molecular Weight535.55
FormulaC26H25F4N3O3S
Cas No.1956435-30-5
SmilesCCOC[C@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(cc1)C(F)(F)F
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (112.03 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8672 mL9.3362 mL18.6724 mL93.3620 mL
5 mM0.3734 mL1.8672 mL3.7345 mL18.6724 mL
10 mM0.1867 mL0.9336 mL1.8672 mL9.3362 mL
20 mM0.0934 mL0.4668 mL0.9336 mL4.6681 mL
50 mM0.0373 mL0.1867 mL0.3734 mL1.8672 mL
100 mM0.0187 mL0.0934 mL0.1867 mL0.9336 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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