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INCB3344 R-isomer

Name: INCB3344 R-isomer
Brand: TargetMol
SKU: T11650
Rating: 4.5 (1 reviews)

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Catalog No. T11650

INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.

INCB3344 R-isomer

😃Good

Catalog No. T11650

INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.

Pack Size	Price	Availability
25 mg	$2,420	3-6 months
50 mg	$3,180	3-6 months
100 mg	$4,300	3-6 months

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Product Introduction

Bioactivity

Description

INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.

Chemical Properties

Molecular Weight	577.59
Formula	C₂₉H₃₄F₃N₃O₆
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 106.5 mg/mL (184.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7313 mL	8.6567 mL	17.3133 mL	86.5666 mL
5 mM	0.3463 mL	1.7313 mL	3.4627 mL	17.3133 mL
10 mM	0.1731 mL	0.8657 mL	1.7313 mL	8.6567 mL
20 mM	0.0866 mL	0.4328 mL	0.8657 mL	4.3283 mL
50 mM	0.0346 mL	0.1731 mL	0.3463 mL	1.7313 mL
100 mM	0.0173 mL	0.0866 mL	0.1731 mL	0.8657 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc