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N-butyryl-L-Homocysteine thiolactone

Name: N-butyryl-L-Homocysteine thiolactone
Brand: TargetMol
SKU: T37342
Rating: 4.5 (1 reviews)

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Catalog No. T37342Cas No. 202284-85-3

N-butyryl-L-Homocysteine thio-lactone, an analog of N-butyryl-L-homoserine lactone, is a small diffusible signaling molecule involved in quorum sensing for controlling gene expression and cellular metabolism. It induces violacein expression in C. violaceum mutants usually not able to produce acylhomoserine lactone (AHL), regulating genes like LuxIR family transcriptional regulators.

N-butyryl-L-Homocysteine thiolactone

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Catalog No. T37342Cas No. 202284-85-3

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$159	35 days	35 days
10 mg	$297	35 days	35 days
25 mg	$686	35 days	35 days
50 mg	$1,130	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	187.26
Formula	C₈H₁₃NO₂S
Cas No.	202284-85-3
Smiles	CCCC(=O)N[C@H]1CCSC1=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: 50 mg/mL (267.01 mM), Sonication is recommended.

Ethanol: 25 mg/mL (133.5 mM), Sonication is recommended.

DMSO: 30 mg/mL (160.21 mM), Sonication is recommended.

PBS (pH 7.2): 0.5 mg/mL (2.67 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	5.3402 mL	26.7008 mL	53.4017 mL	267.0084 mL

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	1.0680 mL	5.3402 mL	10.6803 mL	53.4017 mL
10 mM	0.5340 mL	2.6701 mL	5.3402 mL	26.7008 mL
20 mM	0.2670 mL	1.3350 mL	2.6701 mL	13.3504 mL
50 mM	0.1068 mL	0.5340 mL	1.0680 mL	5.3402 mL
100 mM	0.0534 mL	0.2670 mL	0.5340 mL	2.6701 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-butyryl-L-Homocysteine thiolactoneNbutyrylLHomocysteine thiolactoneN butyryl L Homocysteine thiolactone

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