Shopping Cart

Your shopping cart is currently empty

1R,3S-RSL 3

Name: 1R,3S-RSL 3
Brand: TargetMol
SKU: T9561
Price: 83 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T9561Cas No. 1219810-13-5

1R,3S-RSL 3 is a harmala alkaloid.

1R,3S-RSL 3

Copy Product Info

🥰Excellent

Purity: 99.51%

Catalog No. T9561Cas No. 1219810-13-5

1R,3S-RSL 3 is a harmala alkaloid.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$83	In Stock	In Stock
5 mg	$196	In Stock	In Stock
10 mg	$295	In Stock	In Stock
25 mg	$475	In Stock	In Stock
50 mg	$673	In Stock	In Stock
100 mg	$888	In Stock	In Stock
200 mg	$1,190	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$229	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.51%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

1R,3S-RSL 3 AI Summary

1R,3S-RSL 3 demonstrates cytotoxic activity in various cell lines with AC50 values ranging from 34.2 nM to 1070.0 nM. This compound shows potential as an inhibitor of HRas target activity in these cell-based systems, as indicated by its bioactivity profiles across different assays..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

1R,3S-RSL 3 is a harmala alkaloid.

Chemical Properties

Molecular Weight	440.88
Formula	C₂₃H₂₁ClN₂O₅
Cas No.	1219810-13-5
Smiles	C(CCl)(=O)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C(OC)=O)C4=CC=C(C(OC)=O)C=C4
Relative Density.	1.368 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (124.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2682 mL	11.3410 mL	22.6819 mL	113.4095 mL
5 mM	0.4536 mL	2.2682 mL	4.5364 mL	22.6819 mL
10 mM	0.2268 mL	1.1341 mL	2.2682 mL	11.3410 mL
20 mM	0.1134 mL	0.5670 mL	1.1341 mL	5.6705 mL
50 mM	0.0454 mL	0.2268 mL	0.4536 mL	2.2682 mL
100 mM	0.0227 mL	0.1134 mL	0.2268 mL	1.1341 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc