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MEDI4212

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Catalog No. T9901A-1874 Copy Product Info
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MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. It effectively inhibits human IgE-mediated functional responses, such as calcium signaling, β-hexosaminidase release, and phagocytosis, through its receptor FcεRI. MEDI4212 prevents IgE from binding to CD23 with an IC50 of 8 nM and can be utilized in severe asthma research.

MEDI4212

Pack SizePriceUSA StockGlobal StockQuantity
1 mgInquiryInquiryInquiry
5 mgInquiryInquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. It effectively inhibits human IgE-mediated functional responses, such as calcium signaling, β-hexosaminidase release, and phagocytosis, through its receptor FcεRI. MEDI4212 prevents IgE from binding to CD23 with an IC50 of 8 nM and can be utilized in severe asthma research.
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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