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Azobenzene

Name: Azobenzene
Brand: TargetMol
SKU: T0609
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0609Cas No. 103-33-3

Alias Diphenyldiazene, Diazene

Azobenzene is a phototrigger that can be used to design and synthesize a variety of photoresponsive systems.Azobenzene is genotoxic and induces aggressive sarcomas of the spleen and other abdominal organs.

Azobenzene

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Purity: 99.55%

Catalog No. T0609Alias Diphenyldiazene, DiazeneCas No. 103-33-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.55%

Appearance:Solid

Color:Yellow to Orange

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COA LCMS HNMR

Product Introduction

Azobenzene AI Summary

Azobenzene exhibits a high capacity ratio with a log k'w value of 3.961, indicating good retention on the stationary phase in chromatographic processes, and a logP value of 3.82, suggesting moderate lipophilicity. The compound shows a strong binding affinity to bovine serum albumin with a log 1/C value of 5.29, indicating potential for significant protein binding interactions. Azobenzene does not inhibit 17-alpha-hydroxylase/17,20 lyase from rat testes microsomes at a concentration of 100 μM. It demonstrates bioactivity in assays related to cell viability and metabolic activity with potencies ranging from 631.0 nM to 79432.8 nM. The compound also exhibits inhibitory effects on aldehyde dehydrogenase 1 (ALDH1A1), glucocorticoid receptor signaling, antioxidant response element (ARE) signaling pathway, and human apurinic/apyrimidinic endonuclease 1 (APE1). Additionally, Azobenzene significantly inhibits sodium fluorescein uptake in both OATP1B3-transfected and OATP1B1-transfected CHO cells, with inhibition percentages of 112.1% and 216.34% respectively, at an equimolar substrate-inhibitor concentration of 10 μM. It shows high solubility in water when irradiated with 365 nm UV light for up to 10 minutes and has a half-life of 48 hours in water under these conditions, as determined by UV-Visible spectrum analysis and 1H NMR analysis. These properties suggest that Azobenzene may significantly interact with chromatographic systems, biomolecules, and transporters, influencing its pharmacokinetic and pharmacodynamic profiles..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Azobenzene is a phototrigger that can be used to design and synthesize a variety of photoresponsive systems.Azobenzene is genotoxic and induces aggressive sarcomas of the spleen and other abdominal organs.
Synonyms	Diphenyldiazene, Diazene

Chemical Properties

Molecular Weight	182.22
Formula	C₁₂H₁₀N₂
Cas No.	103-33-3
Smiles	c1ccc(cc1)\N=N\c1ccccc1
Relative Density.	1.09 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (823.18 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4879 mL	27.4394 mL	54.8787 mL	274.3936 mL
5 mM	1.0976 mL	5.4879 mL	10.9757 mL	54.8787 mL
10 mM	0.5488 mL	2.7439 mL	5.4879 mL	27.4394 mL
20 mM	0.2744 mL	1.3720 mL	2.7439 mL	13.7197 mL
50 mM	0.1098 mL	0.5488 mL	1.0976 mL	5.4879 mL
100 mM	0.0549 mL	0.2744 mL	0.5488 mL	2.7439 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc