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Lefradafiban

Name: Lefradafiban
Brand: TargetMol
SKU: T27808
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27808Cas No. 149503-79-7

Alias BIBU-104, BIBU104, BIBU 104

Lefradafiban(BIBU-104) is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.

Lefradafiban

🥰Excellent

Purity: 98.92%

Catalog No. T27808Alias BIBU-104, BIBU104, BIBU 104Cas No. 149503-79-7

Lefradafiban(BIBU-104) is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.

Pack Size	Price	Availability
1 mg	$205	In Stock
5 mg	$497	In Stock
10 mg	$690	In Stock
25 mg	$1,000	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:98.92%

ee:100%

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COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	Lefradafiban(BIBU-104) is an oral platelet glycoprotein IIb/IIIa receptor antagonist for the study of angina pectoris and acute coronary syndromes.
In vivo	Lefradafiban (30, 45, and 60 mg; oral; three times daily for 48 hours; patients with stable angina undergoing angioplasty) is an effective oral glycoprotein IIb/IIIa receptor blocker.[1]
Synonyms	BIBU-104, BIBU104, BIBU 104

Chemical Properties

Molecular Weight	439.46
Formula	C₂₃H₂₅N₃O₆
Cas No.	149503-79-7
Smiles	C(NC(OC)=O)(=N)C1=CC=C(C=C1)C2=CC=C(OC[C@@H]3C[C@@H](CC(OC)=O)C(=O)N3)C=C2
Relative Density.	1.32g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (102.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2755 mL	11.3776 mL	22.7552 mL	113.7760 mL
5 mM	0.4551 mL	2.2755 mL	4.5510 mL	22.7552 mL
10 mM	0.2276 mL	1.1378 mL	2.2755 mL	11.3776 mL
20 mM	0.1138 mL	0.5689 mL	1.1378 mL	5.6888 mL
50 mM	0.0455 mL	0.2276 mL	0.4551 mL	2.2755 mL
100 mM	0.0228 mL	0.1138 mL	0.2276 mL	1.1378 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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