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(4-Acetamidocyclohexyl) nitrate

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Catalog No. T10562Cas No. 137213-91-3
Alias BM121307

(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.

(4-Acetamidocyclohexyl) nitrate

(4-Acetamidocyclohexyl) nitrate

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Catalog No. T10562Alias BM121307Cas No. 137213-91-3
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
In vivo
Following oral administration, 76.5% of BM121307 and its metabolites are eliminated via urine and feces, compared to 80.7% following intravenous administration. The majority of radioactivity is excreted in urine (69.4% and 73.6% of the dose, respectively), with negligible fecal elimination. Urinary analysis indicates that the primary metabolite is trans-N-(4-Hydroxycyclohexyl) acetamide.
SynonymsBM121307
Chemical Properties
Molecular Weight202.21
FormulaC8H14N2O4
Cas No.137213-91-3
SmilesN(C(C)=O)[C@H]1CC[C@H](ON(=O)=O)CC1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

BM-121307BM 121307(4-Acetamidocyclohexyl) Nitrate(4Acetamidocyclohexyl) nitrate(4 Acetamidocyclohexyl) nitrate
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