Shopping Cart

Your shopping cart is currently empty

Ac4GlcNAz

Name: Ac4GlcNAz
Brand: TargetMol
SKU: T205750
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T205750Cas No. 98924-81-3

Alias N-azidoacetylglucosamine-tetraacylated

Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is a cell-permeable azide-functionalized marker of which natural monosaccharide counterpart is GlcNAc, that can observe glycan splicing by the introduction of a fluorescent moiety via click chemistry.

Ac4GlcNAz

😃Good

Purity: 99.93%

Catalog No. T205750Alias N-azidoacetylglucosamine-tetraacylatedCas No. 98924-81-3

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$35	-	In Stock
5 mg	$81	-	In Stock
10 mg	$123	-	In Stock
25 mg	$222	-	In Stock
50 mg	$313	-	In Stock
100 mg	$438	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.93%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is a cell-permeable azide-functionalized marker of which natural monosaccharide counterpart is GlcNAc, that can observe glycan splicing by the introduction of a fluorescent moiety via click chemistry.
In vitro	Ac4GlcNAz is a chemical probe for metabolic O-GlcNAc labeling. In mammalian cells (e.g., PC-3, HeLa, HEK293), Ac4GlcNAz efficiently taken up and converted into UDP-GlcNAz, which is incorporated into proteins by OGT. At 100 μM for 24 hours, labeling is efficient and time- and dose-dependent, as shown by CuAAC detection. However, due to its per-O-acetylated structure, Ac4GlcNAz also causes undesired S-glyco modification on cysteine residues[1].
Synonyms	N-azidoacetylglucosamine-tetraacylated

Chemical Properties

Molecular Weight	430.37
Formula	C₁₆H₂₂N₄O₁₀
Cas No.	98924-81-3
Smiles	O(C(C)=O)[C@@H]1[C@@H](NC(CN=[N+]=[N-])=O)C(OC(C)=O)O[C@H](COC(C)=O)[C@H]1OC(C)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (185.89 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.67 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3236 mL	11.6179 mL	23.2358 mL	116.1791 mL
5 mM	0.4647 mL	2.3236 mL	4.6472 mL	23.2358 mL
10 mM	0.2324 mL	1.1618 mL	2.3236 mL	11.6179 mL
20 mM	0.1162 mL	0.5809 mL	1.1618 mL	5.8090 mL
50 mM	0.0465 mL	0.2324 mL	0.4647 mL	2.3236 mL
100 mM	0.0232 mL	0.1162 mL	0.2324 mL	1.1618 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc