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AF647 carboxylic acid

(Synonyms: AF647 carboxylic acid) Copy Product Info
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Synonyms: AF647 carboxylic acid

Catalog No. T205824 Copy Product Info
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AF 647 carboxylic acid is a fluorescent dye belonging to the AF dye family that emits far-red fluorescence, thereby minimizing spectral overlap and improving resolution in multicolor fluorescence experiments. AF647 carboxylic acid possesses a high quantum yield and generates strong fluorescence signals suitable for high-sensitivity detection and analytical applications. AF647 carboxylic acid demonstrates high solubility in water and most organic solvents, with excitation and emission maxima at 648/671 nm, respectively. AF647 carboxylic acid is extensively utilized in fluorescence imaging, flow cytometry, biomolecular labeling, and high-resolution cellular visualization studies.
AF647 carboxylic acid
Cas No. 407627-58-1
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$195-In Stock
5 mg$483-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:Black
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Product Introduction

Bioactivity
Description
AF 647 carboxylic acid is a fluorescent dye belonging to the AF dye family that emits far-red fluorescence, thereby minimizing spectral overlap and improving resolution in multicolor fluorescence experiments. AF647 carboxylic acid possesses a high quantum yield and generates strong fluorescence signals suitable for high-sensitivity detection and analytical applications. AF647 carboxylic acid demonstrates high solubility in water and most organic solvents, with excitation and emission maxima at 648/671 nm, respectively. AF647 carboxylic acid is extensively utilized in fluorescence imaging, flow cytometry, biomolecular labeling, and high-resolution cellular visualization studies.
In vitro
AF 647 carboxylic acid conjugate to anti-EGFR-AF 647 antibody can visualize the changes in co-localization of theepidermal growth factor (EGF) receptor and clathrin upon EGF addition that are consistent with clathrin-mediated endocytosis in HeLa cells[1].
SynonymsAF647 carboxylic acid
Chemical Properties
Molecular Weight859.02
FormulaC36H46N2O14S4
Cas No.407627-58-1
SmilesO=C(O)CCCCCC1(C=2C=C(C=CC2[N+](=C1C=CC=CC=C3N(C4=CC=C(C=C4C3(C)C)S(=O)(=O)O)CCCS(=O)(=O)O)CCCS(=O)(=O)[O-])S(=O)(=O)O)C
Storage & Solubility Information
StorageKeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: AF647 carboxylic acid chemical structure | AF647 carboxylic acid in vitro | AF647 carboxylic acid formula | AF647 carboxylic acid molecular weight