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N6-Methyl-2'-O-methyladenosine

🥰Excellent
Catalog No. TNU0355Cas No. 57817-83-1
Alias N6,2′-O-Dimethyladenosine

N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine can be used to study obesity and its related diseases.

N6-Methyl-2'-O-methyladenosine

N6-Methyl-2'-O-methyladenosine

🥰Excellent
Purity: 99.97%
Catalog No. TNU0355Alias N6,2′-O-DimethyladenosineCas No. 57817-83-1
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine can be used to study obesity and its related diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$64In StockIn Stock
5 mg$155In StockIn Stock
10 mg$247In StockIn Stock
25 mg$422In StockIn Stock
50 mg$595In StockIn Stock
100 mg$862-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine can be used to study obesity and its related diseases.
SynonymsN6,2′-O-Dimethyladenosine
Chemical Properties
Molecular Weight295.29
FormulaC12H17N5O4
Cas No.57817-83-1
SmilesO(C)[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=CN3)O[C@H](CO)[C@H]1O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (186.26 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3865 mL16.9325 mL33.8650 mL169.3251 mL
5 mM0.6773 mL3.3865 mL6.7730 mL33.8650 mL
10 mM0.3387 mL1.6933 mL3.3865 mL16.9325 mL
20 mM0.1693 mL0.8466 mL1.6933 mL8.4663 mL
50 mM0.0677 mL0.3387 mL0.6773 mL3.3865 mL
100 mM0.0339 mL0.1693 mL0.3387 mL1.6933 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

NucleosideAntimetaboliteNucleoside Antimetabolite/AnalogNucleoside AntimetaboliteN6-Methyl-2'-O-methyladenosineFTOAnalog
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