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3-Hydroxykynurenamine Dihydrochloride

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TargetMol
Catalog No. T68182L
Alias 3-OH-Kynurenamine HCl, 3-Hydroxykynurenamine HCl(99362-47-7 Free base)

3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) is an immunomodulatory biogenic amine, an intermediate in the catabolism of amino acids, which induces oxidative damage and promotes cell death.

3-Hydroxykynurenamine Dihydrochloride

3-Hydroxykynurenamine Dihydrochloride

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TargetMol
Purity: 99.69%
Catalog No. T68182LAlias 3-OH-Kynurenamine HCl, 3-Hydroxykynurenamine HCl(99362-47-7 Free base)
3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) is an immunomodulatory biogenic amine, an intermediate in the catabolism of amino acids, which induces oxidative damage and promotes cell death.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$195In StockIn Stock
5 mg$483In StockIn Stock
10 mg$692In StockIn Stock
25 mg$1,080In StockIn Stock
50 mg$1,490In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.69%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) is an immunomodulatory biogenic amine, an intermediate in the catabolism of amino acids, which induces oxidative damage and promotes cell death.
Synonyms3-OH-Kynurenamine HCl, 3-Hydroxykynurenamine HCl(99362-47-7 Free base)
Chemical Properties
Molecular Weight252.04
FormulaC9H14Cl2N2O2
SmilesO=C(C1=C(C(O)=CC=C1)N)CCN.Cl.Cl
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (396.76 mM), Sonication is recommended.
DMSO: 100 mg/mL (396.76 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.9676 mL19.8381 mL39.6762 mL198.3812 mL
5 mM0.7935 mL3.9676 mL7.9352 mL39.6762 mL
10 mM0.3968 mL1.9838 mL3.9676 mL19.8381 mL
20 mM0.1984 mL0.9919 mL1.9838 mL9.9191 mL
50 mM0.0794 mL0.3968 mL0.7935 mL3.9676 mL
100 mM0.0397 mL0.1984 mL0.3968 mL1.9838 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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