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SCN2 is an esterase-responsive prodrug amphiphile, composed of SN38 and di(triazole-[12]ane N3, N) segments linked through a 7-carbon alkyl chain. It exhibits excellent self-assembly and reversible siRNA condensation properties, along with anticancer cell proliferation activity. SCN2 can be utilized in synthesizing nanoparticles for lung cancer drug delivery.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | SCN2 is an esterase-responsive prodrug amphiphile, composed of SN38 and di(triazole-[12]ane N3, N) segments linked through a 7-carbon alkyl chain. It exhibits excellent self-assembly and reversible siRNA condensation properties, along with anticancer cell proliferation activity. SCN2 can be utilized in synthesizing nanoparticles for lung cancer drug delivery. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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