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Lactitol

Name: Lactitol
Brand: TargetMol
SKU: T20576
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20576Cas No. 585-86-4

Alias NSC-231323, NSC231323, NSC 231323, Lactosit Miruhen, D-Lactitol

Lactitol (Lactit) is a agent that acts on the gastrointestinal tract.

Lactitol

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Purity: 99.08%

Catalog No. T20576Alias NSC-231323, NSC231323, NSC 231323, Lactosit Miruhen, D-LactitolCas No. 585-86-4

Lactitol (Lactit) is a agent that acts on the gastrointestinal tract.

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$41	In Stock	In Stock
500 mg	$89	In Stock	In Stock
1 g	$129	-	In Stock
5 g	$316	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.08%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Lactitol AI Summary

Lactitol demonstrates bioactivity by inhibiting the entry of the Ebola virus, with AC50 values ranging from 3981.1 nM to 8912.5 nM, suggesting potential as an inhibitor against Ebola virus entry. However, it exhibits low potency in inhibiting human BSEP activity, with an IC50 value greater than 1000000.0 nM. The compound also inhibits Trypanosoma cruzi trans-sialidase, showing a Km value of 260000.0 nM. Lactitol shows varying antiviral activities against SARS-CoV-2, including a -5.74% inhibition of virus-induced cytotoxicity in Caco-2 cells at 10 µM and a 9.012% inhibition of SARS-CoV-2 3CL-Pro protease at 20 µM. Despite these activities, it shows limited efficacy in other assays, such as HDAC6 inhibition, with inhibition percentages of -25.65% and -12.71% for two different substrates. Additionally, the compound did not exhibit significant binding affinity or bioactivity in assays with AC50 values greater than 30,000 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Lactitol (Lactit) is a agent that acts on the gastrointestinal tract.
Synonyms	NSC-231323, NSC231323, NSC 231323, Lactosit Miruhen, D-Lactitol

Chemical Properties

Molecular Weight	344.31
Formula	C₁₂H₂₄O₁₁
Cas No.	585-86-4
Smiles	O([C@@H]([C@@H]([C@H](CO)O)O)[C@@H](CO)O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Relative Density.	1.69 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (159.74 mM), Sonication is recommended.

H2O: 20 mg/mL (58.09 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9044 mL	14.5218 mL	29.0436 mL	145.2180 mL
5 mM	0.5809 mL	2.9044 mL	5.8087 mL	29.0436 mL
10 mM	0.2904 mL	1.4522 mL	2.9044 mL	14.5218 mL
20 mM	0.1452 mL	0.7261 mL	1.4522 mL	7.2609 mL
50 mM	0.0581 mL	0.2904 mL	0.5809 mL	2.9044 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0290 mL	0.1452 mL	0.2904 mL	1.4522 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc