Edoxaban M4

Name: Edoxaban M4
Brand: TargetMol
SKU: T19873
Rating: 4.5 (1 reviews)

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Catalog No. T19873Cas No. 834919-19-6

Alias UNII-IV344R972X, Edoxaban 4-Carboxylic Acid, D21-2393, D21 2393

D21-2393 subjects received a single-oral-dose of edoxaban 30-90 mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose.

Edoxaban M4

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Catalog No. T19873Alias UNII-IV344R972X, Edoxaban 4-Carboxylic Acid, D21-2393, D21 2393Cas No. 834919-19-6

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Product Introduction

Bioactivity

Description	D21-2393 subjects received a single-oral-dose of edoxaban 30-90 mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose.
Synonyms	UNII-IV344R972X, Edoxaban 4-Carboxylic Acid, D21-2393, D21 2393

Chemical Properties

Molecular Weight	520.99
Formula	C₂₂H₂₅ClN₆O₅S
Cas No.	834919-19-6
Smiles	CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@H](CC[C@@H]1NC(=O)C(=O)Nc1ccc(Cl)cn1)C(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

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