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Alarin (human) acetate

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Catalog No. T83148L

Alarin (human) acetate is a neuropeptide belonging to the hypothalamic galanin family, widely expressed in the central nervous system and peripheral tissues of humans and rodents. It possesses the signal sequence of the GALP precursor peptide and the first five amino acids of mature GALP lacking exon 3 .Alarin exhibits vasoactive, anti-inflammatory, anti-oedematous, and antibacterial properties, alongside central regulatory functions in energy homeostasis, glucose homeostasis, body temperature, and reproductive hormone secretion.

Alarin (human) acetate

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Purity: 99.93%

Catalog No. T83148L

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$140	-	In Stock
5 mg	$310	-	In Stock
10 mg	$467	-	In Stock
25 mg	$794	-	In Stock
50 mg	$1,190	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.93%

Appearance:Solid

Color:White

Resource Download

COA MS HPLC

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	2954.36
Formula	C₁₂₉H₂₀₉N₄₃O₃₇
Smiles	O=C([C@H]1N(CCC1)C([C@@H](NC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](C)NC([C@H]2N(CCC2)C([C@@H](N)C)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N5[C@@H](CCC5)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O.CC(O)=O
Sequence	Ala-Pro-Ala-His-Arg-Ser-Ser-Thr-Phe-Pro-Lys-Trp-Val-Thr-Lys-Thr-Glu-Arg-Gly-Arg-Gln-Pro-Leu-Arg-Ser
Sequence Short	APAHRSSTFPKWVTKTERGRQPLRS

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (33.85 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.3385 mL	1.6924 mL	3.3848 mL	16.9241 mL
5 mM	0.0677 mL	0.3385 mL	0.6770 mL	3.3848 mL
10 mM	0.0338 mL	0.1692 mL	0.3385 mL	1.6924 mL
20 mM	0.0169 mL	0.0846 mL	0.1692 mL	0.8462 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Alarin(human)acetate（909409865Freebase）