Emedastine Difumarate

Name: Emedastine Difumarate
Brand: TargetMol
SKU: T21388
Rating: 4.5 (1 reviews)

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Catalog No. T21388Cas No. 87233-62-3

Alias Rapimine, KB-2413, KB 2413, Emedastine fumarate, DSSTox_CID_26911, AL-3432A

Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva.

Emedastine Difumarate

😃Good

Catalog No. T21388Alias Rapimine, KB-2413, KB 2413, Emedastine fumarate, DSSTox_CID_26911, AL-3432ACas No. 87233-62-3

Pack Size	Price	Availability	Quantity
5 mg	$970	7-10 days

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Product Introduction

Bioactivity

Description	Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva.
Targets&IC50	H2 receptor:49067 nM (Ki), H3 receptor:12430 nM (Ki), H1 receptor:1.3 nM (Ki)
Synonyms	Rapimine, KB-2413, KB 2413, Emedastine fumarate, DSSTox_CID_26911, AL-3432A

Chemical Properties

Molecular Weight	534.56
Formula	C₂₅H₃₄N₄O₉
Cas No.	87233-62-3
Relative Density.	no data available

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: Insoluble DMSO: Soluble

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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