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2,4-Hexadienal
🥰Excellent
Catalog No. TN9747Cas No. 80466-34-8
2,4-Hexadienal is a high purity biochemical reagent that can be used in research related to life sciences.
2,4-Hexadienal
🥰Excellent
Catalog No. TN9747Cas No. 80466-34-8
2,4-Hexadienal is a high purity biochemical reagent that can be used in research related to life sciences.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 2,4-Hexadienal is a high purity biochemical reagent that can be used in research related to life sciences. |
| In vivo | In F344N rats and B6C3F1 mice, oral gavage of 2,4-Hexadienal (45–240 mg/kg, 16 days to 2 years) caused significant toxicity and carcinogenicity. At 240 mg/kg for 16 days, forestomach necrosis and ulceration were observed, and hyperplasia appeared at 80 mg/kg. After 14 weeks, 120 mg/kg induced forestomach hyperplasia and nasal olfactory epithelial necrosis. Long-term (2-year) exposure led to squamous cell papilloma and carcinoma in the forestomach of rats (45, 90 mg/kg) and mice (120 mg/kg), with oral squamous carcinoma also seen in two male mice. Mechanistic studies suggested tumorigenesis is related to oxidative stress and glutathione depletion[1]. |
| Molecular Weight | 96.13 |
| Formula | C6H8O |
| Cas No. | 80466-34-8 |
| Smiles | O=CC=CC=CC |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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