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Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and lung cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 155.00 | |
5 mg | In stock | $ 472.00 | |
10 mg | In stock | $ 690.00 | |
25 mg | In stock | $ 1,080.00 | |
50 mg | In stock | $ 1,460.00 | |
100 mg | In stock | $ 1,970.00 |
Description | Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and lung cancer. |
In vitro | Tremelimumab exhibits a higher binding affinity for CTLA-4-Ig compared to CD28-Ig, demonstrating specificity for cynomolgus monkeys and humans. It does not engage with human leukocyte FcγR, mitigating the risk of cytokine release syndrome. Interestingly, Tremelimumab enhances IL-2 production in a concentration-dependent manner when stimulated with staphylococcal enterotoxin A, showcasing its ability to modulate T-cell responses.[1] |
Synonyms | Ticilimumab, CP-675206 |
Molecular Weight | N/A |
CAS No. | 745013-59-6 |
store at low temperature
store at -20°C
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Tremelimumab 745013-59-6 Others Ticilimumab CP 675206 CP675206 CP-675206 inhibitor inhibit