Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,520.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator. |
In vitro | Nrf2 activator-7 exhibits binding affinity to Keap1 with an IC50 value of 85 nM as determined by fluorescence polarization (FP) and an IC50 value of 13.1 nM as measured by time-resolved fluorescence energy transfer (TR-FRET), with a Ki value of 4.9 nM [1]. Furthermore, Nrf2 activator-7 at concentrations of 1, 10, and 100 μM over 24 hours increases the transcription of Nrf2 target genes (GSTM3, HMOX1, and NQO1) [1]. |
Molecular Weight | 720.77 |
Formula | C35H32N2O11S2 |
CAS No. | 2456295-39-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Nrf2 activator-7 2456295-39-7 inhibitor inhibit