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Mal-β-CD

Name: Mal-β-CD
Brand: TargetMol
SKU: T19159
Rating: 4.5 (1 reviews)

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Catalog No. T19159Cas No. 104723-60-6

Alias 6-O-alpha-D-Maltosyl-beta-cyclodextrin

Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.

Mal-β-CD

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Catalog No. T19159Alias 6-O-alpha-D-Maltosyl-beta-cyclodextrinCas No. 104723-60-6

Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$42	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.
In vitro	Mal-β-CD effectively extracts cholesterol from cells by forming inclusion complexes. This reduction in cellular cholesterol triggered by Mal-β-CD is restored through the introduction of a cholesterol/Mal-β-CD inclusion complex, which replenishes the cholesterol levels without inducing cytotoxicity.
Synonyms	6-O-alpha-D-Maltosyl-beta-cyclodextrin

Chemical Properties

Molecular Weight	1459.27
Formula	C₅₄H₉₀O₄₅
Cas No.	104723-60-6
Smiles	OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](OC[C@H]3O[C@@H]4O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]5[C@H](O)[C@@H](O)C(O[C@@H]5CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]3[C@H](O)[C@H]4O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.	1.89 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 60.5 mg/mL (41.46 mM), Sonication is recommended.

DMSO: 100 mg/mL (68.53 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	0.6853 mL	3.4264 mL	6.8527 mL	34.2637 mL
5 mM	0.1371 mL	0.6853 mL	1.3705 mL	6.8527 mL
10 mM	0.0685 mL	0.3426 mL	0.6853 mL	3.4264 mL
20 mM	0.0343 mL	0.1713 mL	0.3426 mL	1.7132 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0137 mL	0.0685 mL	0.1371 mL	0.6853 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Mal-β-CDMal-beta-CDMal-b-CD6OαMaltosylβcyclodextrin6-O-α-D-Maltosyl-β-cyclodextrin6-O-a-D-Maltosyl-b-cyclodextrin6 O α Maltosyl β cyclodextrin