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Anti-Her2/ERBB2 Antibody (9I942)
😃Good
Catalog No. TMAY-00037
Alias erb-b2 receptor tyrosine kinase 2, EGFR2
Anti-Her2/ERBB2 Antibody (9I942) is a Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody (9I942) can be used in WB.
Anti-Her2/ERBB2 Antibody (9I942)
Anti-Her2/ERBB2 Antibody (9I942)
😃Good
Catalog No. TMAY-00037Alias erb-b2 receptor tyrosine kinase 2, EGFR2
Anti-Her2/ERBB2 Antibody (9I942) is a Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody (9I942) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: WB Reactivity: Human |
| Alias | erb-b2 receptor tyrosine kinase 2, EGFR2 |
| Ig Type | Mouse IgG2b |
| Clone | 9I942 |
| Reactivity | Human |
| Verified Activity | Anti-ERBB2 mouse monoclonal antibody at 1:500 dilution. -Lane A: SK-BR-3 Whole Cell Lysate. -Lane B: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:138 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Her2/ERBB2 (rh Her2/ERBB2; TMPY-04538; NP_004439.2; Lys676-Val1255). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Her2/ERBB2 Protein (TMPY-04538) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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