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Amatuximab (Synonyms: MORab-009)
Catalog No. T76671 Copy Product Info
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Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
Amatuximab
Copy Product Info🥰Excellent
Catalog No. T76671
Synonyms MORab-009
Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
Amatuximab
Cas No. 931402-35-6
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $198 | In Stock | In Stock | |
| 5 mg | $538 | In Stock | In Stock | |
| 10 mg | $863 | - | In Stock | |
| 25 mg | $1,290 | - | In Stock | |
| 50 mg | $1,760 | - | In Stock | |
| 100 mg | $2,380 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.2% (SDS-PAGE); 98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors. |
| In vitro | Amatuximab (MORAb-009) is a murine-human chimeric monoclonal antibody with selective affinity for mesothelin (MSLN). In vitro, Amatuximab can induce antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cell lines expressing mesothelin and inhibit heterotypic cell adhesion between mesothelin-positive tumor cells and tumor cells expressing CA125[1]. |
| In vivo | In tumor xenograft studies, the combination treatment of Amatuximab and chemotherapy significantly reduces the growth of mesothelin-expressing tumors to a greater extent compared to the use of Amatuximab or chemotherapy alone[1]. |
| Synonyms | MORab-009 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Mesothelin |
| Molecular Weight | 144.31 kDa |
| Cas No. | 931402-35-6 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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