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Amatuximab
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Catalog No. T76671Cas No. 931402-35-6
Alias MORab-009
Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
Amatuximab
Amatuximab
😃Good
Catalog No. T76671Alias MORab-009Cas No. 931402-35-6
Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $198 | In Stock | In Stock | |
| 5 mg | $538 | In Stock | In Stock | |
| 10 mg | $863 | - | In Stock | |
| 25 mg | $1,290 | - | In Stock | |
| 50 mg | $1,760 | - | In Stock | |
| 100 mg | $2,380 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95.2% (SDS-PAGE); 98.4% (SEC-HPLC)
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| Description | Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors. |
| In vitro | Amatuximab (MORAb-009) is a murine-human chimeric monoclonal antibody with selective affinity for mesothelin (MSLN). In vitro, Amatuximab can induce antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cell lines expressing mesothelin and inhibit heterotypic cell adhesion between mesothelin-positive tumor cells and tumor cells expressing CA125[1]. |
| In vivo | In tumor xenograft studies, the combination treatment of Amatuximab and chemotherapy significantly reduces the growth of mesothelin-expressing tumors to a greater extent compared to the use of Amatuximab or chemotherapy alone[1]. |
| Synonyms | MORab-009 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Mesothelin |
| Molecular Weight | 144.31 kDa |
| Cas No. | 931402-35-6 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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