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Nurr1 agonist 8

Name: Nurr1 agonist 8
Brand: TargetMol
SKU: T81632
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T81632Cas No. 360778-55-8

Nurr1 agonist 8 is a low-affinity Nurr1 agonist that can be used to study neurological diseases such as Parkinson's.

Nurr1 agonist 8

🥰Excellent

Purity: 99.79%

Catalog No. T81632Cas No. 360778-55-8

Nurr1 agonist 8 is a low-affinity Nurr1 agonist that can be used to study neurological diseases such as Parkinson's.

Pack Size	Price	Availability
5 mg	$40	In Stock
10 mg	$56	In Stock
25 mg	$98	In Stock
50 mg	$147	In Stock
100 mg	$228	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.79%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Nurr1 agonist 8 is a low-affinity Nurr1 agonist that can be used to study neurological diseases such as Parkinson's.

Chemical Properties

Molecular Weight	297.13
Formula	C₁₄H₁₀Cl₂O₃
Cas No.	360778-55-8
Smiles	OC(=O)C1=CC(OCC2=C(Cl)C=C(Cl)C=C2)=CC=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (336.55 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3655 mL	16.8277 mL	33.6553 mL	168.2765 mL
5 mM	0.6731 mL	3.3655 mL	6.7311 mL	33.6553 mL
10 mM	0.3366 mL	1.6828 mL	3.3655 mL	16.8277 mL
20 mM	0.1683 mL	0.8414 mL	1.6828 mL	8.4138 mL
50 mM	0.0673 mL	0.3366 mL	0.6731 mL	3.3655 mL
100 mM	0.0337 mL	0.1683 mL	0.3366 mL	1.6828 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc