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ART-CHEM-BB B025267

Name: ART-CHEM-BB B025267
Brand: TargetMol
SKU: T9821
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9821Cas No. 381208-40-8

ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.

ART-CHEM-BB B025267

🥰Excellent

Purity: 99.19%

Catalog No. T9821Cas No. 381208-40-8

ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$183	In Stock
10 mg	$272	In Stock
25 mg	$413	In Stock
50 mg	$580	In Stock
100 mg	$777	In Stock
200 mg	$1,030	In Stock
1 mL x 10 mM (in DMSO)	$175	In Stock

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Batch Information

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Purity:99.19%

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Product Introduction

Bioactivity

Description	ART-CHEM-BB B025267 is the upregulator of utrophin production with EC50 of 1.8 μM and can be used in research on the treatment of Duchenne muscular dystrophy.
Targets&IC50	Utrophin:1.8 μM (EC50)

Chemical Properties

Molecular Weight	295.38
Formula	C₁₇H₂₁N₅
Cas No.	381208-40-8
Smiles	CCN(CC)C1=CC=C(C=C1)N1N=C2C=C(C)C(N)=CC2=N1
Relative Density.	1.20 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (186.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3855 mL	16.9273 mL	33.8547 mL	169.2735 mL
5 mM	0.6771 mL	3.3855 mL	6.7709 mL	33.8547 mL
10 mM	0.3385 mL	1.6927 mL	3.3855 mL	16.9273 mL
20 mM	0.1693 mL	0.8464 mL	1.6927 mL	8.4637 mL
50 mM	0.0677 mL	0.3385 mL	0.6771 mL	3.3855 mL
100 mM	0.0339 mL	0.1693 mL	0.3385 mL	1.6927 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc