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Anti-VE-Cadherin Antibody (5N517)

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Catalog No. TMAY-03166
Alias cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody (5N517) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (5N517) can be used in ELISA.

Anti-VE-Cadherin Antibody (5N517)

Anti-VE-Cadherin Antibody (5N517)

😃Good
Catalog No. TMAY-03166Alias cadherin 5, type 2 (vascular endothelium)
Anti-VE-Cadherin Antibody (5N517) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (5N517) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-VE-Cadherin Antibody (5N517) is a Rabbit antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody (5N517) can be used in ELISA.
Aliascadherin 5, type 2 (vascular endothelium)
Ig Type
Monoclonal Rabbit IgG
Clone
5N517
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse VE-Cadherin / CD144 / CDH5 (rM VE-Cadherin / CD144 / CDH5; TMPY-01237; NP_033998.2; Met1-Ala592).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse VE-Cadherin / CD144 / CDH5 protein (TMPY-01237)
Antigen Species
Mouse
Biology Area
Hemangioblast Markers, Cardiac Stem Cell Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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