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2,5-Anhydro-D-mannitol

Name: 2,5-Anhydro-D-mannitol
Brand: TargetMol
SKU: T37783
Rating: 4.5 (1 reviews)

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Catalog No. T37783Cas No. 41107-82-8

2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.

2,5-Anhydro-D-mannitol

😃Good

Catalog No. T37783Cas No. 41107-82-8

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	164.16
Formula	C₆H₁₂O₅
Cas No.	41107-82-8
Smiles	OC[C@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30 mg/mL (182.75 mM), Sonication is recommended.

Ethanol: 5 mg/mL (30.46 mM), Sonication is recommended.

DMF: 25 mg/mL (152.29 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (60.92 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/PBS (pH 7.2)/DMF/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0916 mL	30.4581 mL	60.9162 mL	304.5809 mL
5 mM	1.2183 mL	6.0916 mL	12.1832 mL	60.9162 mL
10 mM	0.6092 mL	3.0458 mL	6.0916 mL	30.4581 mL
20 mM	0.3046 mL	1.5229 mL	3.0458 mL	15.2290 mL

PBS (pH 7.2)/DMF/DMSO

	1mg	5mg	10mg	50mg
50 mM	0.1218 mL	0.6092 mL	1.2183 mL	6.0916 mL

DMF/DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0609 mL	0.3046 mL	0.6092 mL	3.0458 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2,5-Anhydro-D-mannitol2,5AnhydroDmannitol2,5 Anhydro D mannitol