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Fenoxycarb

Name: Fenoxycarb
Brand: TargetMol
SKU: T19803
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19803Cas No. 72490-01-8

Alias Pyctyl, Insegar, Ethyl 2-(4-phenoxyphenoxy)ethylcarbamate

Fenoxycarb (Insegar) is an insecticide against mosquitoes.

Fenoxycarb

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Purity: 97.01%

Catalog No. T19803Alias Pyctyl, Insegar, Ethyl 2-(4-phenoxyphenoxy)ethylcarbamateCas No. 72490-01-8

Fenoxycarb (Insegar) is an insecticide against mosquitoes.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$35	In Stock	In Stock
100 mg	$56	In Stock	In Stock
200 mg	$81	-	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.01%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Fenoxycarb AI Summary

Fenoxycarb is a multi-functional chemical agent exhibiting a broad range of bioactivities and environmental effects. It demonstrates high aqueous solubility with a Log S value of -4.7 and lipophilicity with a LogP value of 4.07. As an inhibitor of human FAAH at a concentration of 1 μM, it achieves an inhibition rate of 13.77%. Additionally, it exerts significant influence in various signaling pathways; notably, it inhibits ROR gamma transcriptional activity, antagonizes estrogen receptor alpha signaling, and acts as an agonist for retinoid X receptor alpha and p53 signaling pathways. It also affects ARE signaling, and both rat and human pregnane X receptor pathways. In agricultural and environmental applications, Fenoxycarb exhibits potent insecticidal properties. It shows 100% ovicidal activity against Cydia pomonella (codling moth) eggs at 0.5 mg/ml topically and nearly 99% when sprayed at 5 mg/ml at ~19°C. It has demonstrated effectiveness against different life stages of Cacopsylla melanoneura in apple plants, achieving mortality rates from 3.3% to 100%. Furthermore, it interferes with metamorphosis in Pyrrhocoris apterus (red firebug) nymphs with ID50 values of 0.2 μg (oral) and 0.09 μg (topical). Moreover, Fenoxycarb mimics juvenile hormone activity in Bemisia tabaci (sweet potato whitefly), suppressing adult and nymph emergence, and in Pieris brassicae (cabbage white butterfly) fifth-instar larvae, causing morphogenetic changes with an ID50 of 21.0 ng. It also blocks the interaction between CBF-beta and RUNX1, a potential therapeutic pathway for acute myeloid leukemia..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fenoxycarb (Insegar) is an insecticide against mosquitoes.
Synonyms	Pyctyl, Insegar, Ethyl 2-(4-phenoxyphenoxy)ethylcarbamate

Chemical Properties

Molecular Weight	301.34
Formula	C₁₇H₁₉NO₄
Cas No.	72490-01-8
Smiles	CCOC(=O)NCCOc1ccc(Oc2ccccc2)cc1
Relative Density.	1.148 g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (199.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3185 mL	16.5926 mL	33.1851 mL	165.9255 mL
5 mM	0.6637 mL	3.3185 mL	6.6370 mL	33.1851 mL
10 mM	0.3319 mL	1.6593 mL	3.3185 mL	16.5926 mL
20 mM	0.1659 mL	0.8296 mL	1.6593 mL	8.2963 mL
50 mM	0.0664 mL	0.3319 mL	0.6637 mL	3.3185 mL
100 mM	0.0332 mL	0.1659 mL	0.3319 mL	1.6593 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc