Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MRT-83 (hydrochloride) is a potent antagonist of the Smoothened (Smo) receptor, effectively inhibiting the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. With its potential applications in the study of cancer disease, MRT-83 (hydrochloride) demonstrates promising prospects for research purposes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 82.00 |
Description | MRT-83 (hydrochloride) is a potent antagonist of the Smoothened (Smo) receptor, effectively inhibiting the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. With its potential applications in the study of cancer disease, MRT-83 (hydrochloride) demonstrates promising prospects for research purposes. |
In vitro | MRT-83 (hydrochloride) (compound 86) demonstrates biological activity with IC50 values of 15 nM and 11 nM in Shh-light2 and C3H10T1/2 cell assays, respectively[1]. |
Molecular Weight | 575.06 |
Formula | C31H31ClN4O5 |
CAS No. | 1359944-60-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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