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8-Nitroguanine

Name: 8-Nitroguanine
Brand: TargetMol
SKU: T36697
Rating: 4.5 (1 reviews)

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Catalog No. T36697Cas No. 168701-80-2

8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.

8-Nitroguanine

😃Good

Catalog No. T36697Cas No. 168701-80-2

8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$296	35 days	35 days
5 mg	$1,200	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.

Chemical Properties

Molecular Weight	196.12
Formula	C₅H₄N₆O₃
Cas No.	168701-80-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

1 M NaOH: 50 mg/mL (254.95 mM), Sonication is recommended.

Solution Preparation Table

1 M NaOH

	1mg	5mg	10mg	50mg
1 mM	5.0989 mL	25.4946 mL	50.9892 mL	254.9460 mL
5 mM	1.0198 mL	5.0989 mL	10.1978 mL	50.9892 mL
10 mM	0.5099 mL	2.5495 mL	5.0989 mL	25.4946 mL
20 mM	0.2549 mL	1.2747 mL	2.5495 mL	12.7473 mL
50 mM	0.1020 mL	0.5099 mL	1.0198 mL	5.0989 mL
100 mM	0.0510 mL	0.2549 mL	0.5099 mL	2.5495 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc