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Anticonvulsant agent 2

🥰Excellent
Catalog No. T73586Cas No. 75220-84-7

Anticonvulsant agent 2 is a potent, orally active anticonvulsant demonstrating antiepileptic activity in a drug-resistant epilepsy model.

Anticonvulsant agent 2

Anticonvulsant agent 2

🥰Excellent
Purity: 98.37%
Catalog No. T73586Cas No. 75220-84-7
Anticonvulsant agent 2 is a potent, orally active anticonvulsant demonstrating antiepileptic activity in a drug-resistant epilepsy model.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$50In Stock
25 mg$103In Stock
50 mg$165In Stock
100 mg$248In Stock
200 mg$345In Stock
1 mL x 10 mM (in DMSO)$41In Stock
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Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.37%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Anticonvulsant agent 2 is a potent, orally active anticonvulsant demonstrating antiepileptic activity in a drug-resistant epilepsy model.
In vivo
Anticonvulsant agent 2 (50 mg/kg, p.o.) decreased motor activity in rats with 21.01% inhibition.[1]
Anticonvulsant agent 2 (50 mg/kg ; p.o.) showed antiepileptic activity with an inhibition rate of 24.45% in rats.[1]
Chemical Properties
Molecular Weight332.83
FormulaC21H17ClN2
Cas No.75220-84-7
SmilesClC1=CC=C(C=2CC(NC=3C(N2)=CC=CC3)C4=CC=CC=C4)C=C1
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 112.5 mg/mL (338.0 mM ), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0045 mL15.0227 mL30.0454 mL150.2268 mL
5 mM0.6009 mL3.0045 mL6.0091 mL30.0454 mL
10 mM0.3005 mL1.5023 mL3.0045 mL15.0227 mL
20 mM0.1502 mL0.7511 mL1.5023 mL7.5113 mL
50 mM0.0601 mL0.3005 mL0.6009 mL3.0045 mL
100 mM0.0300 mL0.1502 mL0.3005 mL1.5023 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Keywords

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