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Arnicolide C

Name: Arnicolide C
Brand: TargetMol
SKU: TN1404
Price: 176 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1404Cas No. 34532-67-7

Alias ArnicolideC

Arnicolide C (Isobutyroylplenolin) is a sesquiterpene lactone metabolite naturally found in Centipeda minima and Arnica montana. Arnicolide C is reported to possess diverse biological activities, including anti-inflammatory, antiallergy, antitumor, anticancer, and antiprotozoal properties, making it a multifunctional natural product.

Arnicolide C

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Purity: 99.99%

Catalog No. TN1404Alias ArnicolideCCas No. 34532-67-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$176	-	In Stock
5 mg	$463	-	In Stock
10 mg	$666	-	In Stock
25 mg	$987	-	In Stock
50 mg	$1,380	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.99%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Arnicolide C (Isobutyroylplenolin) is a sesquiterpene lactone metabolite naturally found in Centipeda minima and Arnica montana. Arnicolide C is reported to possess diverse biological activities, including anti-inflammatory, antiallergy, antitumor, anticancer, and antiprotozoal properties, making it a multifunctional natural product.
In vitro	One of the sesquiterpenes, 6-O-senesioylplenolin (2), is a new pseudoguaianolide sesquiterpene lactone, which was isolated along with known pseudoguaianolide, Arnicolide C (1). The two sesquiterpenes exhibited significant antiallergy activity in passive cutaneous anaphylaxis (PCA) tests. An amide isolated along with the sesquiterpenes was identified as aurantiamide acetate (3).
Synonyms	ArnicolideC

Chemical Properties

Molecular Weight	334.41
Formula	C₁₉H₂₆O₅
Cas No.	34532-67-7
Smiles	O(C(C(C)C)=O)[C@H]1[C@]2([C@@](C[C@@H](C)[C@]3([C@@]1(C)C(=O)C=C3)[H])(OC(=O)[C@H]2C)[H])[H]
Relative Density.	1.16 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (239.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9903 mL	14.9517 mL	29.9034 mL	149.5171 mL
5 mM	0.5981 mL	2.9903 mL	5.9807 mL	29.9034 mL
10 mM	0.2990 mL	1.4952 mL	2.9903 mL	14.9517 mL
20 mM	0.1495 mL	0.7476 mL	1.4952 mL	7.4759 mL
50 mM	0.0598 mL	0.2990 mL	0.5981 mL	2.9903 mL
100 mM	0.0299 mL	0.1495 mL	0.2990 mL	1.4952 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc