Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) compound that effectively suppresses PCSK-9 transcription. It proves promising in the investigation of hyperlipidemia and cardiovascular disease (CVD).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | Inquiry | |
5 mg | Inquiry | Inquiry |
Description | Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) compound that effectively suppresses PCSK-9 transcription. It proves promising in the investigation of hyperlipidemia and cardiovascular disease (CVD). |
In vitro | Inclisiran, a double-stranded small RNA molecule, functions by inhibiting the transcription of proprotein convertase subtilisin kexin 9 (PCSK-9). This action decreases PCSK-9 levels in hepatocytes, which in turn enhances the expression of low-density lipoprotein (LDL) receptors on hepatocyte membranes. As a result, circulating levels of LDL cholesterol (LDL-C) are reduced[1]. |
Synonyms | ALN-PCSsc |
Molecular Weight | N/A |
CAS No. | 1639324-58-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Inclisiran 1639324-58-5 ALN-PCSsc inhibitor inhibit