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Lobenzarit sodium

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Catalog No. T20800Cas No. 64808-48-6
Alias CCA

Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.

Lobenzarit sodium

Lobenzarit sodium

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🥰Excellent
Purity: 99.35%
Catalog No. T20800Alias CCACas No. 64808-48-6
Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$32In StockIn Stock
5 mg$50In StockIn Stock
10 mg$83In StockIn Stock
25 mg$167In StockIn Stock
50 mg$252In StockIn Stock
100 mg$378In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.35%
Appearance:Solid
Color:White
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Product Introduction

Lobenzarit sodium AI Summary
Lobenzarit sodium demonstrates significant antiviral properties. It blocks the entry of the Ebola virus, showing potency in the nanomolar to micromolar range, by inhibiting different channels involved in the virus entry process. Additionally, it exhibits antiviral activity against SARS-CoV-2. In Caco-2 cells, it inhibits SARS-CoV-2 induced cytotoxicity at a concentration of 10 µM after 48 hours, with an inhibition rate of 0.73%. In VERO-6 cells, it shows a 0.09% inhibition rate at the same concentration and exposure time. Lobenzarit sodium also targets SARS-CoV-2's 3CL-Pro protease, which is crucial for viral replication, with an inhibition percentage of 1.042% at a 20 µM concentration..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.
SynonymsCCA
Chemical Properties
Molecular Weight335.65
FormulaC14H8ClNNa2O4
Cas No.64808-48-6
SmilesO=C(C1=C(NC2=CC(Cl)=CC=C2C([O-])=O)C=CC=C1)[O-].[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Slightly soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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