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Anti-HER3/ERBB3 Antibody (9G946) (Synonyms: erb-b2 receptor tyrosine kinase 3)
Catalog No. TMAY-03515 Copy Product Info
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Anti-HER3/ERBB3 Antibody (9G946) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (9G946) can be used in ELISA.
Anti-HER3/ERBB3 Antibody (9G946)
Copy Product Info🥰Excellent
Catalog No. TMAY-03515
Synonyms erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody (9G946) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (9G946) can be used in ELISA.
Anti-HER3/ERBB3 Antibody
(9G946)
(9G946)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-HER3/ERBB3 Antibody (9G946) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (9G946) can be used in ELISA. |
| Synonyms | erb-b2 receptor tyrosine kinase 3 |
| Ig Type | Rabbit IgG |
| Clone | 9G946 |
| Reactivity | Mouse |
| Specificity | Mouse HER3/ERBB3 No cross-reactivity in ELISA with Human ERBB3 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse HER3 / ErbB3 (rM HER3 / ErbB3; TMPY-02365; Q61526; Met1-His641). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse HER3 / ErbB3 protein (TMPY-02365) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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