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Uk-390957

Name: Uk-390957
Brand: TargetMol
SKU: T34994
Price: 60 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T34994Cas No. 364321-71-1

Alias Uk390957, Uk 390957

Uk-390957 is a sulfonamide compound with a high BPR due to binding to carbonic anhydrase.

Uk-390957

🥰Excellent

Purity: 97.07%

Catalog No. T34994Alias Uk390957, Uk 390957Cas No. 364321-71-1

Uk-390957 is a sulfonamide compound with a high BPR due to binding to carbonic anhydrase.

Pack Size	Price	Availability
1 mg	$60	In Stock
5 mg	$151	In Stock
10 mg	$223	In Stock
25 mg	$361	In Stock
50 mg	$523	In Stock
100 mg	$735	In Stock
200 mg	$993	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:97.07%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Uk-390957 is a sulfonamide compound with a high BPR due to binding to carbonic anhydrase.
Targets&IC50	SERT:<= 0.1 µM, SERT:0.004 µM
Synonyms	Uk390957, Uk 390957

Chemical Properties

Molecular Weight	352.47
Formula	C₁₆H₂₀N₂O₃S₂
Cas No.	364321-71-1
Smiles	O(C1=C(CN(C)C)C=C(S(N)(=O)=O)C=C1)C2=CC=C(SC)C=C2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (156.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8371 mL	14.1856 mL	28.3712 mL	141.8560 mL
5 mM	0.5674 mL	2.8371 mL	5.6742 mL	28.3712 mL
10 mM	0.2837 mL	1.4186 mL	2.8371 mL	14.1856 mL
20 mM	0.1419 mL	0.7093 mL	1.4186 mL	7.0928 mL
50 mM	0.0567 mL	0.2837 mL	0.5674 mL	2.8371 mL
100 mM	0.0284 mL	0.1419 mL	0.2837 mL	1.4186 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc