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Anti-CDH17/LI Cadherin Polyclonal Antibody
Catalog No. TMAB-04152 Copy Product Info
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Anti-CDH17/LI Cadherin Polyclonal Antibody is a Rabbit antibody targeting CDH17/LI Cadherin. Anti-CDH17/LI Cadherin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CDH17/LI Cadherin Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04152
Anti-CDH17/LI Cadherin Polyclonal Antibody is a Rabbit antibody targeting CDH17/LI Cadherin. Anti-CDH17/LI Cadherin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CDH17/LI Cadherin Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Antigen Details
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| Description | Anti-CDH17/LI Cadherin Polyclonal Antibody is a Rabbit antibody targeting CDH17/LI Cadherin. Anti-CDH17/LI Cadherin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse) |
| Verified Activity | 1. Sample: Lane 1: Human FHC cell Lysates Lane 2: Human LOVO cell Lysates Lane 3: Human SW480 cell Lysates Primary: Anti-LI Cadherin (TMAB-04152) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kDa Observed band size: 130 kDa 2. Sample: SW480 (Human) Cell Lysate at 30 μg Primary: Anti-LI Cadherin (TMAB-04152) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 130 kD 3. Paraformaldehyde-fixed, paraffin embedded (rat colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (LI Cadherin) Polyclonal Antibody, Unconjugated (TMAB-04152) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded (rat small intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (LI Cadherin) Polyclonal Antibody, Unconjugated (TMAB-04152) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein (Potential). |
| Tissue Specificity | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. Similarity : Contains 7 cadherin domains. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
| Immunogen | KLH conjugated synthetic peptide: human LI-cadherin |
| Antigen Species | Human |
| Gene Name | CDH17 |
| Gene ID | |
| Protein Name | Cadherin-17 |
| Uniprot ID | |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
| Molecular Weight | Theoretical: 90 kDa. Actual: 130 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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