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ABMDMA

Name: ABMDMA
Brand: TargetMol
SKU: T64957
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: 9,10-Anthracenediyl-bis(methylene)dimalonic acid) Copy Product Info

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Synonyms: 9,10-Anthracenediyl-bis(methylene)dimalonic acid

Catalog No. T64957 Copy Product Info

Purity: 95.17%

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ABMDMA (9,10-Anthracenediyl-bis(methylene)dimalonic acid) is a chemical probe and indicator with photobleaching properties that can be photobleached by mono-linear oxygen to the corresponding peroxylactone, and can be used to determine photo-induced mono-linear oxygen generation (SOG).

Cas No. 307554-62-7

Pack Size	Price	USA Stock	Global Stock
25 mg	$40	-	In Stock
50 mg	$64	-	In Stock
100 mg	$106	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:95.17%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	ABMDMA (9,10-Anthracenediyl-bis(methylene)dimalonic acid) is a chemical probe and indicator with photobleaching properties that can be photobleached by mono-linear oxygen to the corresponding peroxylactone, and can be used to determine photo-induced mono-linear oxygen generation (SOG).
In vitro	I. Singlet oxygen generation (SOG) measurement 1. Solution preparation: Dissolve ABMDMA in a suitable solvent (such as DMSO or aqueous buffer) at a working concentration of 1-10uM. Make sure the concentration of the probe is suitable for the specific experimental needs. 2. Singlet oxygen generation: Expose the sample to light (usually UV or visible light) to induce the generation of singlet oxygen. 3. Monitoring: After irradiation, measure the fluorescence or absorbance changes of ABMDMA to monitor singlet oxygen generation. The photobleaching changes of ABMDMA due to the reaction with singlet oxygen can directly reflect the generation of singlet oxygen. II. Photochemical and photophysical studies 1. Excitation: Excite ABMDMA in the sample with an appropriate light source to excite the anthracene group. 2. Detection of photobleaching: Monitor the fluorescence quenching or absorbance changes caused by the reaction of singlet oxygen with ABMDMA. 3. Analysis: Calculate the photobleaching rate and the extent of singlet oxygen generation from the data. III. Photosensitizer study 1. Introduce ABMDMA into the photosensitizer system and illuminate the system. 2. Measure the photobleaching rate of ABMDMA to quantitatively evaluate the generation of singlet oxygen. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands.
Synonyms	9,10-Anthracenediyl-bis(methylene)dimalonic acid

Chemical Properties

Molecular Weight	410.37
Formula	C₂₂H₁₈O₈
Cas No.	307554-62-7
Smiles	O=C(O)C(C(=O)O)CC1=C2C=CC=CC2=C(C=3C=CC=CC31)CC(C(=O)O)C(=O)O

Storage & Solubility Information

Storage

Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 83.33 mg/mL (203.06 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 8.33 mg/mL (20.3 mM), Solution.

10% DMSO+90% Saline: < 8.33 mg/mL (20.3 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4368 mL	12.1841 mL	24.3683 mL	121.8413 mL
5 mM	0.4874 mL	2.4368 mL	4.8737 mL	24.3683 mL
10 mM	0.2437 mL	1.2184 mL	2.4368 mL	12.1841 mL
20 mM	0.1218 mL	0.6092 mL	1.2184 mL	6.0921 mL
50 mM	0.0487 mL	0.2437 mL	0.4874 mL	2.4368 mL
100 mM	0.0244 mL	0.1218 mL	0.2437 mL	1.2184 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: ABMDMA chemical structure | ABMDMA in vitro | ABMDMA formula | ABMDMA molecular weight