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Seniprutug

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Catalog No. T9901A-1503Cas No. 2484772-72-5

Seniprutug (BCD-180) is a humanized monoclonal antibody targeting T cell receptor beta variable 9 (TRBV9). It selectively depletes pathogenic T cell clones expressing TRBV9 via antibody-dependent cellular cytotoxicity (ADCC), representing a highly promising precision targeted therapeutic strategy for studying autoimmune diseases such as ankylosing spondylitis.

Seniprutug

Seniprutug

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Catalog No. T9901A-1503Cas No. 2484772-72-5
Seniprutug (BCD-180) is a humanized monoclonal antibody targeting T cell receptor beta variable 9 (TRBV9). It selectively depletes pathogenic T cell clones expressing TRBV9 via antibody-dependent cellular cytotoxicity (ADCC), representing a highly promising precision targeted therapeutic strategy for studying autoimmune diseases such as ankylosing spondylitis.
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Product Introduction

Bioactivity
Description
Seniprutug (BCD-180) is a humanized monoclonal antibody targeting T cell receptor beta variable 9 (TRBV9). It selectively depletes pathogenic T cell clones expressing TRBV9 via antibody-dependent cellular cytotoxicity (ADCC), representing a highly promising precision targeted therapeutic strategy for studying autoimmune diseases such as ankylosing spondylitis.
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetTRBV9
Chemical Properties
Cas No.2484772-72-5
Antibody Information
IsotypeIgG1-REM
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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