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Anti-EGFR Antibody (4I461) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (4I461) can be used in IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
| Description | Anti-EGFR Antibody (4I461) is a Mouse antibody targeting EGFR. Anti-EGFR Antibody (4I461) can be used in IF,IHC,WB. |
| Synonyms | PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10 |
| Clone | 4I461 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Hela cell lysate, using TMAC-01250 diluted at 1:1,000. ![]() |
| Application | |
| Recommended Dose | WB dilution: 1:1000 ;IF dilution:1:100-200 ; IHC: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Affinity purification using immunogen. |
| Appearance | Liquid |
| Formulation | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Actual: 170 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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