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KD6001
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Catalog No. T9901A-1747 Copy Product Info
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KD6001 is a humanized IgG1κ monoclonal antibody targeting CTLA4. It effectively disrupts the interaction between CTLA-4 and CD80 (IC50: 16 ng/mL) as well as CD86. KD6001 enhances the expression of IL-2 and IFNγ in PHA-activated human lymphocytes, demonstrating potent antitumor activity. It significantly inhibits tumor growth in mouse models with MC38, B16, and Hepa1-6 tumors. KD6001 is applicable in cancer research, including studies on advanced melanoma, hepatocellular carcinoma, and liver cancer.
KD6001
Cas No. 2983061-18-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | -$1 | Inquiry | Inquiry | |
| 5 mg | -$1 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Storage & Solubility Information
| Description | KD6001 is a humanized IgG1κ monoclonal antibody targeting CTLA4. It effectively disrupts the interaction between CTLA-4 and CD80 (IC50: 16 ng/mL) as well as CD86. KD6001 enhances the expression of IL-2 and IFNγ in PHA-activated human lymphocytes, demonstrating potent antitumor activity. It significantly inhibits tumor growth in mouse models with MC38, B16, and Hepa1-6 tumors. KD6001 is applicable in cancer research, including studies on advanced melanoma, hepatocellular carcinoma, and liver cancer. |
| Cas No. | 2983061-18-1 |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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