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HMBR

Name: HMBR
Brand: TargetMol
SKU: T77752
Price: 75 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77752Cas No. 1287651-36-8

Alias 4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)-

HMBR are not fluorescent by themselves, but when combined with Y-FAST, they emit yellow light when excited by blue light.

HMBR

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Purity: 99.79%

Catalog No. T77752Alias 4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)-Cas No. 1287651-36-8

HMBR are not fluorescent by themselves, but when combined with Y-FAST, they emit yellow light when excited by blue light.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$75	In Stock	In Stock
5 mg	$183	In Stock	In Stock
10 mg	$297	In Stock	In Stock
25 mg	$596	In Stock	In Stock
50 mg	$953	In Stock	In Stock
100 mg	$1,520	In Stock	In Stock
200 mg	$1,980	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.79%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	HMBR are not fluorescent by themselves, but when combined with Y-FAST, they emit yellow light when excited by blue light.
In vitro	Instructions for use I. Solution preparation 1. Stock solution: The recommended concentration is 10–50 mM (adjustable according to experimental needs). Dissolve it in sterile water or buffer and mix until completely dissolved. Notes: Powder: Store at -20°C or lower in a light-proof, dry environment; Solution: Store at 4°C for short term, and store at -20°C for long term in aliquots and light-proof conditions to avoid repeated freezing and thawing. II. Operation steps (taking oxidation reaction as an example) 1. Prepare the reaction system: buffer (such as 50 mM Tris-HCl, pH 7.4). 2. Add HMBR stock solution to the working concentration (usually 1–5 mM). 3. Add enzymes or other reactants (such as peroxide). 4. Control reaction conditions: Temperature: 37°C. Time: 10–30 minutes, the specific time is optimized according to the experiment. 5. Detection method: Use a spectrophotometer to measure the absorbance or chemical signal of the reaction product. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands.
Synonyms	4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)-

Chemical Properties

Molecular Weight	251.32
Formula	C₁₁H₉NO₂S₂
Cas No.	1287651-36-8
Smiles	C(=C/1\SC(=S)NC1=O)\C2=CC(C)=C(O)C=C2

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 237.5 mg/mL (945.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9790 mL	19.8950 mL	39.7899 mL	198.9495 mL
5 mM	0.7958 mL	3.9790 mL	7.9580 mL	39.7899 mL
10 mM	0.3979 mL	1.9895 mL	3.9790 mL	19.8950 mL
20 mM	0.1989 mL	0.9947 mL	1.9895 mL	9.9475 mL
50 mM	0.0796 mL	0.3979 mL	0.7958 mL	3.9790 mL
100 mM	0.0398 mL	0.1989 mL	0.3979 mL	1.9895 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HMBR